Monica E. Embers obtained her PhD in the Department of Microbiology and Immunology at the Pennsylvania State University College of Medicine in Hershey, PA, where she studied immune responses to Papillomaviruses. She made the transition to the study of bacterial pathogenesis when performing her postdoctoral research on the Lyme disease spirochete at the Tulane National Primate Research Center (TNPRC). She subsequently joined the faculty at the TNPRC. Her research program regarding Borrelia burgdorferi and Lyme disease is designed around two major foci: (1) antibiotic efficacy against Lyme disease; and (2) immunodiagnosis for B. burgdorferi infection and cure. The first research goal is to examine, using xenodiagnosis, the efficacy of antibiotic treatment during disseminated B. burgdorferi infection in the nonhuman primate model of Lyme disease. The second goal is to develop a quantitative multi-antigen test that expands detection limits and helps to distinguish persistent infection from clinical cure. By transmitting Lyme disease to nonhuman primates by tick and studying the natural course of infection, her group hopes to facilitate a better understanding of the clinical quandaries of human Lyme disease, including effective diagnosis and treatment.