Dr. Ying Zhang is a Professor at Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health. His research interests are focused on antibiotic resistance, bacterial persistence, and development of more effective treatments for persistent infections. Although much of his career is on M. tuberculosis, recently, he has been working on the challenging problem of persistent Lyme disease. His group developed a new high throughput assay which allowed identification of a range of FDA-approved drugs that have excellent activity against Borrelia burgdorferi persisters. This finding has generated considerable interest and may offer new opportunity to improve treatment of persistent Lyme. In collaboration with colleagues, he is interested to evaluate the promising candidate drugs in combinations in animal models and also in patients for more effective treatment of Lyme disease.